突击量氯磷定救治重度有机磷中毒临床观察

目的:比较早期突击量与常规量氯磷定对重度急性有机磷农药中毒(AOPP)的救治疗效。方法:对86例重度有机磷农药中毒患者,依据使用氯磷定突击量及常规量方案分为两组,治疗组45例,采用突击量氯磷定治疗;对照组41例,采用常规量氯磷定治疗。结果:治疗组平均住院时间16.4d,治愈率91.1%,病死率8.9%,阿托品平均用量121.3mg;对照组平均住院时间23.7d,治愈率75.6%,病死率24.4%,阿托品平均用量194.4mg;经统计学处理,两组治愈率差异有显著性(P<0.01)。结论:早期突击量氯磷定救治有机磷农药中毒能减少阿托品用量,防治并发症,缩短疗程,提高治愈率。

Clinical Observation of Assault-quantity Pam-Cl in Treating AOPP

Objective Comparing the Therapeutic effect of pam-Cl of assault-quantity used in early time and regular-quantity to rescue AOPP.Methods 86 AOPP are divided into two groups by being given assault-quantity or regular-quantity pam-Cl,there are 45 patients given assault-quantity in the treat group ,while other 41 patients given regular-quantity in the control group.Results The average time of treat group in hospital are 16.4 days,healing rate is 91.1%,death rate is 8.9%,the average doses of atropine are 121.3mg;The average time of control group are 23.7 days , healing rate is 75.6%,death rate is 24.4%,the average doses of atropine are 194.4mg.Through the statistical, theatment the healing rate of two groups has significant deviation(P<0.01).Conclusion Using assault-quantity pam-Cl in early time can decrease the doses of atropine,prevent and cure complications,shorten the course of disease and improve cure rate.