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Late cutaneous reactions in patients with delayed pressure urticaria
Authors:Kathleen C Davis MD  Yoseph A Mekori MD  Peter F Kohler MD  Alan L Schocket MD
Institution:1. Division of Clinical Immunology, Department of Medicine, University of Colorado School of Medicine, Denver, Colo., USA;2. Environmental Care Unit, Presbyterian-St. Luke''s Medical Center, Denver, Colo., USA
Abstract:Late cutaneous reactions ( LCRs ) have been described in patients after allergen skin testing, skin testing with heterologous anti-human IgE, autologous skin-blister fluid, and, variably, after 48/80 injection. We report our results of skin testing patients with delayed pressure urticaria ( DPU ), chronic urticaria, and normal volunteers with histamine and 48/80. All patients with DPU had LCRs after 48/80. No patients in either of the other groups developed LCRs . This may be a clue to pathogenic mechanisms involved in DPU .
Keywords:LCR  Late cutaneous reaction  DPU  Delayed pressure urticaria  CU  Chronic urticaria (delayed pressure negative)  NSAID  Nonsteroidal anti-inflammatory drugs  WFR  Wheal-and-flare reaction  ESR  Erythrocyte sedimentation rate
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