边缘性人格障碍发病机制研究进展

目的回顾最近几年有关边缘性人格障碍的研究,探讨边缘性人格障碍的发病机制。方法应用Medline和中国知网期刊文献检索2008年2月之前关于边缘性人格障碍的相关文献,检索词为边缘性人格障碍(borderline personality disorder)和发病机制(mechanisms)。结果选择以边缘性人格障碍发病机制相关的文献有46篇,分别涉及到边缘性人格障碍的神经传递素、亲附特点、神经成像、遗传学、认知以及分型。结论边缘性人格障碍是指一群异质的个体,他们在症状表现、病因、心理病理机制的反应等方面可能都存在着很大的差异,它是受生物、心理和社会多方面影响的。

Recent Development of Pathogenetic Mechanisms on the Borderline Personality Disorder

Objective To review the study of borderline personality disorder in recent years and discuss the mechanisms of the borderline personality disorder.Methods Medline and CNKI database were used to search the articles about borderline personality disorder before February,2008.Search Words are were borderline personality disorder and mechanisms.Results 46 reference were related to the mechanisms of the borderline personality disorder,and they are about neurotransmission of borderline personality disorder,attachment with BPD,neuroimaging,genetics,cognition and subtypes of BPD.Conclusion The borderline personality disorder is heterogeneous group of individuals,and symptoms,causes,psychological pathological mechanisms may exist great differences biological,which are effected by biology,psychiatry,society and so on.