应用DWI和ADC预测弥漫性轴索损伤患者昏迷时间

目的:探讨磁共振扩散成像(DWI)和表观扩散系数(ADC)在预测弥漫性轴索损伤(DAI)患者昏迷时间的应用。方法:将57例伤后2h~20d、临床与影像诊断均符合弥漫性轴索损伤(DAI)的患者,进行磁共振常规 T1WI、T2WI和DWI检查,在其DWI表观扩散系数图上测定兴趣区ADC值。昏迷时间预测模型的建立采用逐步回归分析。结果:分析结果显示预测模型预测的昏迷时间与患者实际昏迷的时间非常接近。结论:昏迷时间预测模型可为临床提供昏迷时间预测。

Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) in Prediction of Coma Duration of Patients with Diffuse Axonal Injury

Objective:To evaluate the value of diffusion-weighted imaging and apparent diffusion coefficient (ADC) in prediction of coma duration of patients with diffuse axonal injury.Methods:Fifty seven patients were collected in this study.The patients were victims of traffic accidents and were randomly chosen from August 2002 to March 2004.Apparent Diffusion Coefficient Maps were obtained and the mean ADC values of each ROI (Region of Interest)were measured using MRI console software.Conventional MR imaging consisted of spin-echo T 1-weighted imaging and T 2-weighted imaging.Diffusion-weighted imaging was performed using spin-echo echo-plannar sequence.The analysis methods were used logistic regression model for the coma duration prognostication model established.Results:Analysis showed that the predicted coma duration estimation by the prognostication model approximated the real coma duration of the patient.Conclusion:The coma duration prognostication model can prognosticate the duration of coma.