少腹逐瘀汤辅助宫腔镜手术治疗对子宫内膜息肉患者术后复发率的影响

目的 探讨少腹逐瘀汤辅助宫腔镜手术治疗对子宫内膜息肉患者术后复发率的影响。方法 选择2019年6月一2021年1月江苏省常州市武进中医医院收治的子宫内膜息肉患者124例为对象，根据治疗方法不同将患者分为对照组和试验组，每组各62例。对照组采用宫腔镜手术治疗，术后常规给予抗生素预防感染，并于下次月经后半周期即月经来潮后第15天，口服黄体酮胶囊，每次100 mg，每天2次，连续用药15d （1个疗程）。试验组在对照组基础上加用少腹逐瘀汤，连续服用4周。用药4周后评估患者相关指标，并完成12个月随访，比较两组症状消失时间、子宫内膜厚度、血浆黏度、纤维蛋白原、月经量，以及治疗后6、12个月的妊娠率及复发率。结果 试验组治疗后月经量增多、倦怠无力、五心烦热、面色晦暗及小腹疼痛症状消失时间均显著短于对照组（P<0.05）；两组治疗4周后子宫内膜厚度、血浆黏度、纤维蛋白原、月经量均显著低于本组治疗前（P<0.05）；试验组治疗4周后子宫内膜厚度、血浆黏度、纤维蛋白原、月经量均显著低于对照组（P<0.05）；随访12个月，试验组妊娠率显著高于对照组（P<0.05）；复发率显著低于对照组（P<0.05）。结论 宫腔镜手术后加用少腹逐瘀汤能显著缩短子宫内膜息肉患者症状消失时间，改善子宫内膜厚度及血液流变学水平，可调节患者月经量，提升患者妊娠率，降低复发率，值得推广应用。

Application of Shaofu Zhuyu Decoction in hysteroscopic surgery for endometrial polyps and its effect on postoperative recurrence rate

Objective To investigate the clinical effect of Shaofu Zhuyu Decoction in hysteroscopic surgery for patients with endometrial polyps and its effect on postoperative recurrence rate.Methods A total of 124 patients with endometrial polyps from June 2019 to January 2021 were selected as the subjects, and they were randomly divided into two groups with 62 cases in each group.Patients in the control group were treated with hysteroscopic surgery, antibiotics were routinely given to prevent infection after operation, and Progesterone Capsules were taken orally twice a day, 100 mg each time, for 15 days(one course of treatment) in the second half of the next menstrual cycle, i.e.the 15 th day after menstruation.Patients in experimental group were treated with Shaofu Zhuyu Decoction for four weeks on the basis of the control group.After four weeks of medication, the patient''s relevant indicators were evaluated and 12 months of follow-up were completed.The time of symptom disappearance, endometrial thickness, plasma viscosity, fibrinogen, menstrual volume, pregnancy rate and recurrence rate of six and 12 months after treatment were compared between the two groups.Results After treatment, the disappearance time of menstruation increased, fatigue and weakness, five heart trouble, dimmish and darkish complexion, and abdominal pain symptoms in the experi mental test groupwere significantly shorter than those in the control group(P<0.05).After four weeks of tre atment, the endometrial thickness, plasma viscosity, fibrinogen and menstrual volume of the two groups were significantly lower than those before treatment(P<0.05).After four weeks of treatment, the endometrial thickness, plasma viscosity, fibrinogen and menstrual volume in the experimental group were significantly lower than those in the control group(P<0.05).After 12 months of follow-up, the pregnancy rate in the experimental group was significantly higher than that in the control group(P<0.05), and the recurrence rate was significantly lower than that of the control group(P<0.05).Conclusion The addition of Shaofu Zhuyu Decoction after hysteroscopy can significantly shorten the time of symptom disappearance in patients with endometrial polyps, improve the thickness of endometrium and the level of hemorheology, regulate the menstrual volume of patients, increase the pregnancy rate of patients, and reduce the recurrence rate, which is worth popularizing.