早期肠内营养治疗重症急性胰腺炎的临床疗效及安全性分析

目的研究早期肠内营养治疗重症急性胰腺炎的临床疗效及安全性。方法60例重症急性胰腺炎患者,随机分为对照组和研究组,各30例。研究组进行早期肠内营养治疗,对照组进行延迟肠内营养治疗。观察比较两组患者治疗后的急性生理学及慢性健康状况评分系统Ⅱ(APACHEⅡ)评分、住院时间及并发症发生率。结果研究组治疗后APACHEⅡ评分(6.09±1.02)分明显低于对照组的(8.93±1.78)分,住院时间(16.35±4.15)d明显短于对照组的(26.17±3.96)d,差异有统计学意义(P<0.05)。研究组并发症发生率3.33%低于对照组的20.00%,差异有统计学意义(P<0.05)。结论对于重症急性胰腺炎患者,早期肠内营养治疗可以进一步提高临床疗效及安全性,缩短患者住院时间,还可以进一步减少并发症发生,值得推广。

Clinical efficacy and safety of early enteral nutrition in the treatment of severe acute pancreatitis

Objective To study the clinical efficacy and safety of early enteral nutrition in the treatment of severe acute pancreatitis.Methods A total of 60 patients with severe acute pancreatitis were randomly divided into control group and research group,with 30 cases in each group.The research group was treated with early enteral nutrition,and the control group was treated with delayed enteral nutrition.The acute physiology and chronic health evaluationⅡ(APACHEⅡ)score before and after treatment,hospitalization time and incidence of complications were compared between the two groups.Results After treatment,the APACHEⅡscore(6.09±1.02)points of the research group was obviously lower than(8.93±1.78)points of the control group,and hospitalization time(16.35±4.15)d was obviously shorter than(26.17±3.96)d of the control group,and the difference was statistically significant(P<0.05).The incidence of complications 3.33%of the research group was lower than 20.00%of the control group,and the difference was statistically significant(P<0.05).Conclusion For severe acute pancreatitis,early enteral nutrition therapy can further improve clinical efficacy and safety,shorten hospitalization time,and further reduce the occurrence of complications.It is worthy of promotion.