清幽愈疡汤治疗幽门螺杆菌阳性消化性溃疡35例临床观察

目的:观察清幽愈疡汤治疗幽门螺杆菌(Hp)阳性消化性溃疡(PU)的疗效。方法:70例Hp阳性消化性溃疡患者随机分为两组,治疗组口服清幽愈疡汤4周,对照组采用三联疗法,口服奥美拉唑4周、阿莫西林和替硝唑1周。观察两组疗效、溃疡面缩小、Hp根除率、不同证型疗效、疗效稳定性等。结果:治疗组和对照组愈显率分别为82.9%、77.1%,两组在疗效及溃疡缩小差异均无显著性(P>0.05),复发率和Hp根除率差异有显著性(P<0.05),治疗组不同证型疗效差异无显著性(P>0.05),未见不良反应。结论:清幽愈疡汤治疗Hp阳性PU有较好疗效,复发率低、Hp清除率高、疗效稳定。

Clinical Observation on 35 Cases of Positive Peptic Ulcer with Helicobacter Pylori Treated by Qingyouyuyang Decoction

Objective:To observe the therapeutic effect of Peptic Ulcer with HP treated by Qingyouyang Decoction.Methods:70 cases were randomly divided into two groups,35 cases in each group.Treatment group took Qingyouyuyang Decoction orally for four weeks.Control group treated by the Triple Therapeutic Method:taking oral administration of omeprazole for four weeks,while amoxicillin and tinidazole for one week.To observe the therapeutic effect and narrowing ulcer's surface,HP clearance rate and different syndrome types' efficacy,stability and security of curative effect were investigated in both groups.Results:With no adverse reaction,the cured & markedly effective rate of the treatment group and the control group are 82.9% and 77.1% respectively;The two groups also have no significant differences both in therapeutic effects and narrowing ulcer's surface(P>0.05),but they have significant differences in relapse rate and HP clearance rate(P<0.05);The therapeutic effect of different syndrome types in treatment group has no significant differences(P>0.05).Results:PU treated by Qingyouyuyang Decoction has a good therapeutic effect,low relapse rate,high HP clearance rate.And the different syndrome types of HU treated by Qingyouyuyang Decoction in a modified dialectical way,with a trait stability and security of therapeutic effect.