自然妊娠和辅助生育技术妊娠双胎的母婴围产期预后

目的比较自然妊娠和辅助生育技术（assisted reproduction technology,ART）妊娠双胎的母婴围产期预后。方法选择北京协和医院定期随诊并分娩的双胎211例,其中自然妊娠142例,ART妊娠69例,回顾性分析两组孕妇一般情况、围产期并发症、分娩情况及新生儿并发症。结果 ART组孕妇年龄[（34.23±4.13）岁]大于自然妊娠组孕妇[（32.02±4.45）岁],P〈0.05。两组孕妇围产期并发症的发生率差异无统计学意义（P〉0.05）;②ART组新生儿平均孕龄小于自然妊娠组,（251.87±15.16）d比（256.04±12.26）d,且新生儿感染发生率低,5（3.7%）比26（9.4%）,P〈0.05。结论与自然妊娠双胎相比,ART双胎妊娠不增加孕妇围产期并发症的风险,而且新生儿健康状态与自然妊娠双胎相当。

Perinatal outcomes of twin pregnancies among cases of spontaneous conception and assisted reproduction technology

Objective The aim of this study was to evaluate and compare the perinatal and neonatal outcomes of assisted reproduction technology（ART）twin pregnancies and those of spontaneously conceived twin pregnancies（SC）.Methods The medical files of ART and naturally conceived twin pregnancies were studied retrospectively.Data concerning maternal characteristics,obstetric complications and neonatal outcomes were recorded and compared.Results Mean maternal age was higher in ART group than in SC group[（34.23±4.13）ys vs（32.02±4.45）ys,P0.05）].No significant differences were found in obstetric complication between the two groups.The mean gestational age and the incidence of neonatal infection were lower in ART group[（251.87±15.16）days,3.7%]than in SC group[（256.04±12.26）d,9.4%]（P0.05）.Conclusion The obstetric complications and neonatal outcomes have no significant differences in ART twin pregnancies and naturally conceived twin pregnancies.