| 丘脑梗死听觉事件相关电位的研究 |
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| 引用本文： | 付东平,谢炳玓.丘脑梗死听觉事件相关电位的研究[J].天津医药,2007,35(3):177-178. |
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| 作者姓名： | 付东平 谢炳玓 |
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| 作者单位： | 300052,天津医科大学总医院 |
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| 摘 要： | 目的：研究丘脑梗死患者听觉事件相关电位（P300）的变化特点。方法：应用听觉事件相关电位和认知能力筛查量表检测丘脑梗死患者加例（患者组）和健康查体者30例（正常对照组）。结果：患者组P300波潜伏期明显延长（P〈0．01）;P300波波幅降低（P〈0．05），认知能力筛查量表评分也明显下降（P〈0．01）。左侧与右侧丘脑梗死P300波潜伏期、波幅和认知能力检查评分比较差异无统计学意义（P〉0．05）。治疗后随访P300波潜伏期、波幅和认知能力检查评分明显好转，与治疗前比较差异有统计学意义（P〈0．05或P〈0．01）。结论：听觉事件相关电位的检查有利于丘脑梗死认知功能状态的判断及病情变化的观察。
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| 关 键 词： | 丘脑 梗死 事件相关电位 P300 认知 神经心理学 |
| 修稿时间： | 2006-03-302006-10-12 |
Study on Auditory Event-related Potential in Thalamic Infarction |
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| FU Dongping,XIE Bingdi.Study on Auditory Event-related Potential in Thalamic Infarction[J].Tianjin Medical Journal,2007,35(3):177-178. |
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| Authors: | FU Dongping XIE Bingdi |
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| Institution: | Department of lnternal Medicine, General Hospital of Tianjin Medical University, Tianjin 300052, China |
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| Abstract: | Objective: To study the changes of auditory event-related potential (AERP)P300 in patients with thalamic infarction. Methods: Thalamic infarction patients and normal controls were detected by AERP and cognitive ability sifting investigation (CASI). Results: The P300 latency was significantly prolonged (P < 0.01), P300 amplitude decreased (P < 0.05) and CASI decreased significantly in thalamic infarction group. There was no significant difference between left and right groups of thalamic infarction in P300 latency, amplitude and CASI (P > 0.05). P300 latency, amplitude and CASI increased after treatment in follow up (P < 0.05 or P < 0.01). Conclusion: AERP is useful to estimate cognitive state of thalamic infarction and observe the disease. |
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| Keywords: | thalamus infarction event-related potentials P300 cognition neuropsychology |
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