[18F]fluorodeoxyglucose positron emission tomography is a useful tool to diagnose the early stage of Takayasu's arteritis and to evaluate the activity of the disease |
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Authors: | Kunihiko Umekita Ichiro Takajo Syunichi Miyauchi Katoko Tsurumura Siro Ueno Norio Kusumoto Yasufumi Kai Masayuki Kuroki Takashi Sasaki Akihiko Okayama |
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Affiliation: | (1) Department of Internal Medicine, Rheumatology, Infectious Disease and Laboratory Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-0012, Japan |
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Abstract: | Takayasu's arteritis (TA) is a rare disease that can be difficult to diagnose in its early stage. A young woman with a fever and neck pain was thought to have TA, although computed tomographic angiography did not show any specific changes of the arteries. [18F]fluorodeoxyglucose positron emission tomography ([18F]FDG-PET) was performed to detect the source of the inflammation. Specific accumulation of [18F]FDG-6-phosphate in the thoracic aorta and its direct branches was observed, leading to a diagnosis of TA. [18F]FDG-PET is therefore considered to be useful for the diagnosis of early-stage TA. |
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Keywords: | Diagnosis Fever of unknown origin [18F]Fluorodeoxyglucose positron emission tomography ([18F]FDG-PET) Takayasu's arteritis (TA) |
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