病毒性肝炎重叠感染综合分析

目的：研究探讨病毒性肝炎重叠感染患者的病情转归及治疗情况；方法：检测１９９０～１９９２年住院病人ＨＶＡ—ＩｇＭ、ＨＢｓＡｇ、抗ＨＢｓ、ＨＢｅＡｇ、抗ＨＣＶ，混合有两种以上病毒标志物者为重叠感染；结果：５６例中男：女＝５．２：１，平均年龄３２．０５岁，单独感染者平均住院３０．１ｄ，重叠感染者５７．２９ｄ，甲乙型重叠感染７５％，乙丙型重叠感染１４．３％，甲乙丙型重叠感染１０．７％，５例重叠丙肝病毒患者使用干扰素治疗效果不理想；结论：病毒性肝炎各型间重叠感染并不少见，输血是丙肝重要传播途径，合并丙肝者病情较单纯感染重，病程迁延，转为慢性肝炎、肝硬变机会多，对丙肝治疗上，尚缺乏有效方法

COMPREHENSIVEANALYSISOFVIRUS HEPATITISOVERLAPPINGINFECTION

objective: Thetreatmentandprognosisoftheoverlappinginfectedvirushepatitisarediscussed.HZMethods: Thisgroupincludestheinpatientsofourhospitalfrom1990to1992.DetectedtheirbloodHVAIgM,HBsAg,antiHBs,HBeAg,antiHCV.Twoormorekindsviralmarkercarriercalledoverlappinginfection.T5,5HZResults: In56insingleinfectedpatientwas30.1days,andinoverlappinginfectedpatientwas57.29days.TheoverlappinginfectionofTypeAandBmakesup75%,TypeBandCmakesup14.3%,andTypeA,BandCamountsto10.7%.Interferonwasusedin5casesofoverlappinginfectionwithTypeCvirushepatitis.Thecurativeeffectwasnotsatisfied. Conclusion:WT5,5BZTheoverlappinginfectionofvarioustypesofvirushepatitisisnotrare.HematometachysisisoneofthemainrouteoftransmissionofTypeCvirushepatitis.Thepatientscases,theratioofmaletofemaleis5.2to1.Themeanageis32.05years.ThemeantimeofhospitalizationcombinedwithTypeCaremuchmoreseriousthansingleinfectedones.Theyusuallyhaveprotractedcourseofdisease,andhavemorechanceconversetochronichepatitisorhepatocirthosis.ThereisnoeffcctivetreatmentforTypeCvi