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低能量氦—氖激光对周围神经再生的影响
引用本文:石凯军 吕荣. 低能量氦—氖激光对周围神经再生的影响[J]. 中国修复重建外科杂志, 1997, 11(1): 14-18
作者姓名:石凯军 吕荣
作者单位:第四军医大学西京医院全军骨科研究所
摘    要:用44只体重2.5kg的家兔作实验,分4,8,12及16周4个观察照射线各用6只,对照且各用兔5只。麻醉后,均切断左侧腓总神经,用9/0尼龙单丝对端吻合神经外膜。照射组在术后1d开始用8318-B型低能量氦-氖激光仪经皮肤照射L5,6脊髓节段,每天照射15min,共照射14d。

关 键 词:激光疗法 轴突再生 周围神经损伤

INFLUENCE OF LOW ENERGY HE NE LASER ON REGENERATION OF PERIPHERAL NERVE/
Abstract:The purpose of this experiment was to elucidate the influence of the low energy He Ne laser on the function of regeneration of peripheral nerve. Forty four rabbits about 2.5kg body weight were used in the experiment. The animals were divided into 4, 8, 12, 16 weeks groups according to the observation period. Six animals were used in each irradiated group and in the control group 5 rabbits were used in each observation period. regeneration of the axon and myelinc sheath, the latent rate of the common peroneal nerve, the conditions of the anterior tibital muscle and the toe expansion test were all observed systematically in both groups. The experimental results was: A few thin regenerated axon was seen at 4 weeks in the irradiated group, while in the control group it might be seen at 8 weeks, the P value was <0.01. A low amplitude latent rate of the common peroneal nerve is determined at the peroneal side of the anterior tibial muscle in a few animal at 4 weeks of the irradiated group, and it is not observed in the control group, from 12 to 16 weeks. THe latent rate of the common peroneal nerve was the irradiated group than in the controlled, the P value was <0.01. The regeneration of the myeline sheath was evident in the irradiated group, and also the slstion of the musdle fibers anterior tibial muscle was clearly visible than the controlled. 16 weeks postoperatively, the toe expansion test was normal in the irradiated group, while in the control group it was the same as seen at 12 weeks after operation in the irradiated group. Now it was certain that the low energy He Ne laser could promole the function of the spinal motor nerve cells and accelerate the axonal regeneration.
Keywords:He Ne laser Axonal regeneration Latent rate Toe expansion test  
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