军人肠易激综合征患者的人格特征、应对方式和C反应蛋白水平

目的分析军事环境中肠易激综合征(IBS)患者伴有抑郁、焦虑情绪及其人格和应对方式,观察C反应蛋白(CRP)水平探讨炎症对IBS患者的发病机制的作用,提高对IBS认识。方法对符合诊断IBS的439人,应用抑郁量表、焦虑量表、艾森克人格问卷及应对方式问卷进行心理测查,检验CRP。分析其人格、应对方式,结合情绪状况和大便异常状况对伴有或不伴有抑郁、焦虑症状者的CRP水平进行分析。结果①IBS的发生率为16.0%,CRP阳性率者为9.8%,结合阳性结果的反应幅度,有抑郁、焦虑情绪者8.88%为阳性,不伴有抑郁焦虑情绪者0.91%为阳性;②IBS患者有抑郁和(或)焦虑情绪为88.4%,其中抑郁为17.5%,便秘者为主要表现,占44.2%;焦虑22.0%,大便次数增多为主要表现,占60.4%;同时伴有抑郁和焦虑者为48.7%,大便次数增多和便秘表现为49.1%、50.9%;CRP阳性似乎更容易在同时伴抑郁焦虑、或大便次数增多[44.2%(19/43)]的IBS患者中发生;③与常模比较IBS患者情绪稳定性有显著差异;④在伴有抑郁和(或)焦虑情绪改变时,积极应对和消极应对选择与常模比较有显著差异,无抑郁、焦虑情绪改变的应对方式无变化。结论社会心理因素与炎症因子标志物(CRP)水平不能排除其有相关性。在心理机制,情绪的稳定性和积极的应对方式对于IBS的发病时是重要影响因素,发生与植物神经功能异常有关的功能性胃肠病。

Analysis on the personality,coping style and CRP levels of IBS armyman patients

Objective To analyse military environments associated depression,anxiety mood and personality and coping style of IBS patients,combined with the observation C-reactive protein(CRP) level.To further explore the important role of the inflammation in the pathogenesis of IBS patients so as to increase the awareness about IBS.Methods To the 439 persons meeting the diagnosis,Selfrated depression scale(SDS),Selfrated anxiety scale(SAS),Eysenck personality questionnaire(EPQ) and characteristic coping style Questionnaires(CSQ) psychological testing and inspection of questionnaire CRP were taken to analyse their personality,coping style,and combined with emotional condition and fecal anomaly to the persons with or without associated depression and anxiety symptoms to analyse their CRP levels.Results 1)The overall alarm rate was 16.0% on IBS,masculine rate was 9.8% on CRP,combined with the depression and anxiety of masculine rate was 8.88%,without associated depression and anxiety of masculine rate was 0.91%;2)IBS patients with depression or(and) anxiety was 88.4%,including depression had 17.5%,constipation was the main manifestations of 44.2%;anxiety was 22.0%,loose stools was the main manifestations of 60.4%,combined with the depression and anxiety of was 48.7%,loose stools and constipation was the main manifestations of 49.1% and 50.9%.Combined with the depression and anxiety or increased stool of IBSpatients seems easierly happen CRP positive;3)IBS patients had significant deviation emotional stability than the normal person;4)Depression or(and) anxiety then positivecoping and negativecoping changes had significant deviation than the normal person,without associated depression or anxiety of positivecoping and negativecopingdid not change than the normal person.Conclusion Social psychic factor and inflammatory factor marker(CRP) do not removed having associativity.In the psychological mechanisms,emotional stability and positivecoping for IBS episode are the important influencing factors inducing autonomic nerve concerned functional gastrointestinal disorders.