Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene. |
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Authors: | J A Menendez L Vellon R Lupu |
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Affiliation: | Department of Medicine, Breast Cancer Translational Research Program, Evanston Northwestern Healthcare Research Institute, Evanston, IL, USA. jmenendez@enh.org |
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Abstract: | |
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Keywords: | orlistat fatty acid synthase Her2/neu PEA3 trastuzumab breast cancer |
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