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In-vitro study of Zn uptake in developing rat enamel |
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| Authors: | JW Bawden A Wennberg |
| Institution: | Dental Research Center and Department of Pedodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC, U.S.A. |
| Abstract: | Molar explants from 8-day-old rats were cultured for up to 12h. Addition of calf serum (10 per cent) to the defined medium (M199) markedly reduced 65Zn uptake in enamel. Metabolic inhibition (DNP) or heat killing had no apparent effect on movement of tracer through the enamel organ to the enamel. Removal of the enamel organ prior to culture resulted in increased uptake of 65Zn in the enamel. |
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