防晒系数仪器测定与人体试验测定结果的比较

[目的 ]　论证在测定防晒化妆品的防晒系数时 ,SPF - 2 90型防晒系数分析仪在我国用于评价SPF值的可行性 ,从而明确该仪器法与人体法的相关关系 ,为体外法测定SPF值提供科学依据。　 [方法 ]　选择在日本用人体方式测试过的 9个样品 ,进行两种方法的比较。　 [结果 ]　采用TransporeR1 52 7- 3型膜带 ,用 2 μL/cm2 的量涂布样品 ,在温度为 2 0℃、相对湿度 60 %的实验室环境内放置 2 0min后用SPF - 2 90防晒系数分析仪测试的SPF值与人体试验结果的相关系数为r=0 .9768;同时可根据防晒化妆品在 2 90～ 40 0nm之间的吸收曲线 ,估计产品防护UVA和UVB的能力。　 [结论 ]　SPF - 2 90型防晒系数分析仪在我国可以用于防晒化妆品防晒系数的测定。

Comparison of the sun protection factor(SPF) values measured by SPF-290S Analyzer System and Japanese vivo method

To explore a test method by SPF-290S Analyzer System and provide a scientific rule for the assessment on the function of sunscreen products in vitro. Nine samples collected were tested both in vitro and in Japanese vivo method. With the substrate of Transpore R 1527-3,temperature of 20℃,humidity of 60%,exposural period of 20 minutes and sunscreen quantity of 2μL/cm 2, the sun-protection of both UVA and UVB from the absorbance curve of sunscreens in the wave lengths of 290-400nm were evaluated. The correlation coefficient between in vitro and in vivo was 0.9768. [Conclusion] SPF-290S Analyzer System may be used to assess sunscreen efficacy in our country.