| 寻常性银屑病并发成人型线状IgA大疱性皮病 |
| |
| 引用本文： | 牛军州,王华,付萌,王刚,廖文俊.寻常性银屑病并发成人型线状IgA大疱性皮病[J].临床皮肤科杂志,2010,39(2). |
| |
| 作者姓名： | 牛军州 王华 付萌 王刚 廖文俊 |
| |
| 作者单位： | 1. 中国人民解放军昆明总医院皮肤科工作
2. 第四军医大学西京医院全军皮肤病研究所,陕西西安,710032 |
| |
| 摘 要： | 报告l例寻常性银屑病并发成人型线状IgA大疱性皮病.患者男,36岁.因全身红色斑疹伴白色鳞屑反复发生20年.躯干、双上肢出现环状排列的水疱10d伴瘙痒就诊.皮损组织病理检查:表皮下水疱,疱内、真皮浅层和真皮乳头见中性粒细胞、嗜酸性粒细胞浸润;皮损周围皮肤直接免疫荧光显示基膜带Iga、IgG呈带状沉积;取患者血清行BP180NC16A(大疱性类天疱疮18 000抗原的近膜片段)-ELISA检查显示阴性;以盐裂正常人皮肤为底物,取患者血清行间接免疫荧光检查显示IgA、IgG呈带状沉积在真皮侧.诊断为寻常性银屑病并发成人型线状TgA大疱性皮病.
|
| 关 键 词： | 大疱性皮病 IgA 线状 银屑病 |
A case of psoriasis vulgaris combined with adult linear IgA bullous disease |
| |
| NIU Jun-zhou,WANG Hua,FU Meng,WANG Gang,LIAO Wen-jun.A case of psoriasis vulgaris combined with adult linear IgA bullous disease[J].Journal of Clinical Dermatology,2010,39(2). |
| |
| Authors: | NIU Jun-zhou WANG Hua FU Meng WANG Gang LIAO Wen-jun |
| |
| Abstract: | To report a case of psoriasis vulgaris combined with adult linear Igt bullous disease.A 36-year-old male who presented with a 20 years history of stable chronic psoriasis vulgaris developed linear IgA bullous disease in 10 days,which displayed blister around erythematous plaques.Histology of lesional skin showed subepidermal bulla containing a mixture of inflammatory cells with predominating neutrophils.Direct immunofluorescence of perilesional skin showed linear deposition of IgA and IgG along the basement membrane zone.ELISA of serum with BP280NC16A showed negative.Indirect immunoflores-cence of serum with salt-split normal human skin showed the presence of IgA and IgG auto-antibodies by the side of derma.The cage was rare psoriasis vulgaris complicated by an adult linear IgA bullous disease. |
| |
| Keywords: | bulloas disease IgA linear psoriasis |
| 本文献已被 万方数据 等数据库收录！ |
|
