| Affiliation: | (1) Division of Cardiology, Department of Internal Medicine II, University of Vienna, Austria;(2) Division of Medical Radiation Physics, Department of Radiotherapy and Radiobiology, University of Vienna, Austria |
| Abstract: | This study was performed to evaluate the outcome ofpercutaneous revascularization in  edge restenoses developingafter radioactive stent implantation in de novo and in-stentlesions. Twenty-one consecutive patients undergoing target lesionrevascularization (TLR) at any follow-up after phosphorus-32radioactive stent implantation were included in this study. We assessedthe incidence of death, myocardial infarction, repeated TLR andrecurrent angina over the following 18 months. After 6 months, TLR ratewas 28.6%, and no stent thromboses, deaths or Q-wave myocardialinfarctions occurred. Among the patients with TLR there weresignificantly more subjects who had received a radioactive stent in aprevious in-stent restenosis (66.7% vs. 0% in patients without secondrestenosis; P < 0.001), or who had received tworadioactive stents (83.3% vs. 33.3%; P = 0.038).After 18 months, TLR rate was 33.3%, and two patients (9.5%) haddied. Restenosis after intravascular radiotherapy can be safely treatedby percutaneous interventional techniques, yielding an acceptableclinical result within 18 months. |
