| 小分子整联蛋白结合配体N-连接糖蛋白家族成员在牙髓干细胞分化过程中的作用 |
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| 引用本文： | 霍丽珺,凌均棨.小分子整联蛋白结合配体N-连接糖蛋白家族成员在牙髓干细胞分化过程中的作用[J].国际口腔医学杂志,2008,35(6). |
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| 作者姓名： | 霍丽珺 凌均棨 |
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| 作者单位： | 中山大学口腔医学研究所,广东,广州,510055;中山大学口腔医学研究所,广东,广州,510055 |
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| 摘 要： | 体外诱导牙髓干细胞向成牙本质细胞分化并观察其过程,是目前研究牙髓干细胞分化机制和寻找其分化标志的主要方法。在成牙本质细胞分化和矿化过程中,小分子整联蛋白结合配体N-糖蛋白(SBLING)家族成员发挥着重要作用。下面就SBLING家族成员牙本质涎磷蛋白、牙本质基质蛋白-1和细胞外基质磷酸糖蛋白在牙髓干细胞分化过程中的作用作一综述。
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| 关 键 词： | 小分子整联蛋白结合配体N-糖蛋白家族 牙本质涎磷蛋白 牙本质基质蛋白 细胞外基质磷酸糖蛋白 |
The study of small integrin-binding ligand N-linked glycoproteins family as dental pulp stem cells differentiate |
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| HUO Li-jun,LING Jun-qi.The study of small integrin-binding ligand N-linked glycoproteins family as dental pulp stem cells differentiate[J].Journal of International Stomatology,2008,35(6). |
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| Authors: | HUO Li-jun LING Jun-qi |
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| Abstract: | It is a main method in study of the differentiate mechanism of dental pulp stem cells and looking for the markers for odontoblast differentiation that induces dental pulp stem cells differentiate to odontoblast and survey odontoblast differentiation in vitro. The members of small integrin-binding ligand N-linked glycoproteins family play an important role in the differentiation and mineralization of odontoblast. This is a review of the research progress in small integrin-binding ligand N-linked glycoproteins family as dental pulp stem cells differentiate, including dentin matrix protein-1, dentin sialophosphoprotein, matrix extracellular phosphoglycoprotein. |
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| Keywords: | small integrin-binding ligand N-linked glycoproteins family dentin matrix protein dentin sialophosphoprotein matrix extracellular phosphoglycoprotein |
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