| PRELIMINARY STUDY OF THREE-TONE PARADIGM AUDITORY P300 ON AGING DEMENTIA |
| |
| 引用本文： | 张晓君 赵毅 高玉红 耿稚萍 余华峰. PRELIMINARY STUDY OF THREE-TONE PARADIGM AUDITORY P300 ON AGING DEMENTIA[J]. 中国医学科学杂志(英文版), 2001, 16(3): 153-156 |
| |
| 作者姓名： | 张晓君 赵毅 高玉红 耿稚萍 余华峰 |
| |
| 作者单位： | DepartmentofNeurology,BeijingTongrenHospital,CapitalUniversityofMedicalSciences,Beijing100730 |
| |
| 摘 要： | Objective. To explore the changes of three-tone paradigm P300 and observe the improvement of the diagnostic sensitivity of P300 in aging dementia. Methods. Thirty-four patients of aging dementia underwent traditional P300 (2t-P300) and three-tone paradigm auditory P300 (3t-P300). The results of these two methods were compared. Results. Abnormal P300 was found in 18 of 34 dementia cases (52. 9% ) by 2t-P300, and in 26 of 30 pa-tients who finished the 3t-P300 tests (86. 7% ). In 2t-P300, 9 of 24 mild cases, 7 of 8 moderate cases and 2 severe cases showed abnormal results. In 3t-P300, 20 of 24 mild cases and all 6 moderate cases showed abnormal results. Abnormal 3t-P300 was found in 13 of 16 cases which showed normal 2t-P300. Besides prolonged and bad-shaped P300, no certain response of P300 to rare non-target stimulus (r-nT) was found in 10 mild cases by 3t-P300. Conclusion. Three-tone paradigm auditory P300 had higher sensitivity in early diagnosis of aging dementia than traditional auditory P300. No P300 response to r-nT in 3t-P300 is an important index in early diagnosis of mild dementia.
|
| 关 键 词： | 老年性痴呆 3t-P300 事件相关电位 脑电图 诊断 |
PRELIMINARY STUDY OF THREE-TONE PARADIGM AUDITORY P300 ON AGING DEMENTIA |
| |
| Zhang Xiaojun,Zhao Yi,Gao Yuhong,Geng Zhiping and Yu Huafeng. PRELIMINARY STUDY OF THREE-TONE PARADIGM AUDITORY P300 ON AGING DEMENTIA[J]. Chinese medical sciences journal, 2001, 16(3): 153-156 |
| |
| Authors: | Zhang Xiaojun Zhao Yi Gao Yuhong Geng Zhiping Yu Huafeng |
| |
| Affiliation: | Department of Neurology, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730. |
| |
| Abstract: | OBJECTIVE: To explore the changes of three-tone paradigm P300 and observe the improvement of the diagnostic sensitivity of P300 in aging dementia. METHODS: Thirty-four patients of aging dementia underwent traditional P300 (2t-P300) and three-tone paradigm auditory P300 (3t-P300). The results of these two methods were compared. RESULTS: Abnormal P300 was found in 18 of 34 dementia cases (52.9%) by 2t-P300, and in 26 of 30 patients who finished the 3t-P300 tests (86.7%). In 2t-P300, 9 of 24 mild cases, 7 of 8 moderate cases and 2 severe cases showed abnormal results. In 3t-P300, 20 of 24 mild cases and all 6 moderate cases showed abnormal results. Abnormal 3t-P300 was found in 13 of 16 cases which showed normal 2t-P300. Besides prolonged and bad-shaped P300, no certain response of P300 to rare non-target stimulus (r-nT) was found in 10 mild cases by 3t-P300. CONCLUSION: Three-tone paradigm auditory P300 had higher sensitivity in early diagnosis of aging dementia than traditional auditory P300. No P300 response to r-nT in 3t-P300 is an important index in early diagnosis of mild dementia. |
| |
| Keywords: | event- related potential dementia diagnosis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
