Department of Paediatrics, Hiroshima Red Cross Hospital;Hiroshima Health Administration Center;The Department of Neurosurgery, Hiroshima University School of Medicine, Hiroshima, Japan
Abstract:
ABSTRACT. Pituitary hyperplasia, hypertrichosis and blunted growth hormone (GH) secretion were observed in three children with untreated primary hypothyroidism. These abnormalities disappeared and improved after thyroid hormone therapy. The recognition of these associations may eliminate unnecessary surgery and GH therapy and lead to the choice of thyroid hormone replacement therapy.