| 寻常性银屑病血清MCP-1的检测 |
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| 引用本文： | 唐玲,于益芝,李泉,郭志丽,阎明,郑茂荣. 寻常性银屑病血清MCP-1的检测[J]. 中国皮肤性病学杂志, 2003, 17(2): 87-87,90 |
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| 作者姓名： | 唐玲 于益芝 李泉 郭志丽 阎明 郑茂荣 |
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| 作者单位： | 1. 第二军医大学附属长海医院皮肤科,上海,200433
2. 第二军医大学免疫学研究所,上海,200433 |
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| 基金项目： | 国家自然科学基金 (39970 689)，上海市科技启明星计划资助 (99QB1 4 0 4 7) |
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| 摘 要： | 目的 初步探讨单核细胞趋化因子-1（monocyte chemoattractant protein-1,MCP-1)在银屑病发病机制中的作用。方法 分离处于不同病期的寻常性银屑病患者外周血清，通过酶联免疫吸附（ELISA）法检测银屑病患者血清中MCP-1的水平；同时比较了不同病期中血清MCP-1水平。结果 银屑病患者血清中MCP-1水平明显高于健康对照组，但MCP-1的水平并不随病期的变化而变化。结论 银屑病外周血MCP-1的高表达可能与银屑病的发病有关。
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| 关 键 词： | 寻常性银屑病 血清 MCP－1 检测 |
| 文章编号： | 1001-7089(2003)02-0087-02 |
The Level of MCP-1 in Serum from Psoriasis Vuigaris |
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| TANG Ling,YU Yi-zhi,LI Quan,et al. The Level of MCP-1 in Serum from Psoriasis Vuigaris[J]. The Chinese Journal of Dermatovenereology, 2003, 17(2): 87-87,90 |
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| Authors: | TANG Ling YU Yi-zhi LI Quan et al |
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| Abstract: | Objective To investigate the effects of MCP-1 in the pathogenesis of psoriasis.Methods The concentration of MCP-1 in the serum from psoriasis vulgaris was determined by ELISA and the levels of MCP-1 between the different stages of disease were compared.Results The concentration of MCP-1 in the serum from psoriatic peripheral blood was significantly increased.But the levels of MCP-1 did not change along with the development of disease.Conclusion High levels of MCP-1 in peripheral blood might be related to the pathogenesis of psoriasis. |
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| Keywords: | Psoriasis MCP-1 |
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