| MMP-9在骨肉瘤中的表达及其临床意义 |
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| 引用本文： | 吕红伟,陈猛,李树峰,路青林.MMP-9在骨肉瘤中的表达及其临床意义[J].医学检验与临床,2007,18(3):57-58. |
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| 作者姓名： | 吕红伟 陈猛 李树峰 路青林 |
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| 作者单位： | 山东省千佛山医院骨科,济南,250014 |
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| 摘 要： | 目的研究骨肉瘤组织中基质金属蛋白酶-9(mmp-9)的表达情况,分析其与骨肉瘤肺转移的关系。方法应用免疫组织化学方法检测42例骨肉瘤组织中基质金属蛋白酶-9(mmp-9)的表达。结果非转移组5例阳性、转移组16例阳性、卡方值为9.54,P<0.05。组间有显著差异。结论mmp-9可以作为骨肉瘤发生肺转移的标志物。
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| 关 键 词： | 骨肉瘤 肺转移 基质金属蛋白酶-9 免疫组织化学 |
The Expression of MMP- 9 in Osteosarcoma and its Significance |
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| Lv HongWei,Chen Meng,Li Shufeng,Lu Qinglin.The Expression of MMP- 9 in Osteosarcoma and its Significance[J].Medical Laboratory Science and Clinics,2007,18(3):57-58. |
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| Authors: | Lv HongWei Chen Meng Li Shufeng Lu Qinglin |
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| Abstract: | Objective The aim of the study is to detect the expression of mmp-9 and to analysis the correlation with lung metastasis of osteosarcoma.Method Mmp-9 was detected immunohistochemically in 42 paraffin specimens of 42 classical osteosarcoma patients.Results In 21 specimens,mmp-9 showed positive staining.Conclusions Mmp-9 can be the molecular marker for lung metastasis of osteosarcoma. |
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| Keywords: | Osteosarcoma Lung metastasis mmp-9 Immunohistochemistry |
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