糖尿病早期视网膜神经组织病理性改变研究进展

糖尿病视网膜病变（DR）是主要的致盲眼病。一直认为，视网膜微血管在糖尿病视网膜病理改变中发挥了主导作用。最近研究显示，在DR过程中有神经元的凋亡、神经胶质细胞功能障碍及视觉电生理等改变且先于视网膜微血管病变。本文综述近年来DR视网膜神经组织的国内外研究进展。

Neuronal and Glial Dysfunction before Diabetic Retinopathy (review)

Diabetic retinopathy is the leading cause of blindness in those of working age. It is well known that the retinal vasculature is altered during diabetes. More recently, it has emerged that neuronal, glial dysfunction and electroretinogram changes occur in those with diabetes. Current research is directed at understanding these neuronal and glial changes because they may be an early manifestation of disease processes that ultimately lead to vascular abnormality. This review will highlight the recent advances in our understanding of the neuronal, glial dysfunction, electroretiongram changes that occur during diabetes.