Psychoactive substance use disorder in relatives of patients with anorexia nervosa. |
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Authors: | S L Stern K N Dixon R A Sansone M D Lake E Nemzer D Jones |
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Institution: | Department of Psychiatry, Ohio State University, Columbus 43210-1228. |
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Abstract: | We assessed the lifetime prevalence and morbid risk of psychoactive substance use disorder (SUD; alcoholism and drug use disorder) in the first- and second-degree relatives, excluding children, of 34 female patients with anorexia nervosa (AN) and 34 age- and sex-matched controls who had no history of an eating disorder. Diagnoses of relatives were made blind to probands' diagnoses. The prevalence of SUD was 9% in both anorectic and control relatives, and the figures for morbid risk were 14% and 15%, respectively; these differences were nonsignificant. These results suggest that adolescent and adult women with AN do not possess many of the familial factors that predispose to the development of psychoactive SUD. |
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