| 钩吻对环磷酰胺化疗小鼠的造血保护作用 |
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| 引用本文： | 黄兰青 王坤 余尚扬 周利元 赵丽娟. 钩吻对环磷酰胺化疗小鼠的造血保护作用[J]. 右江民族医学院学报, 1994, 16(4): 5-7 |
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| 作者姓名： | 黄兰青 王坤 余尚扬 周利元 赵丽娟 |
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| 作者单位： | Huang Lanqing Wang kun She Shangyang Zhou Liyuan Zhao Lijuan Department of Microbiology，Youjiang Medical for National Minorities Bose，Guangxi，China |
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| 摘 要： | 用钩吻乙醇粗提物对小鼠肉瘤１８０（Ｓ１８０）生长抑制实验结果表明，其对Ｓ１８０无明显抑制作用，也未显示出能增强环磷酰胺（Ｃｙ）的抗瘤效应，但能明显减慢Ｃｙ化疗所致白细胞下降的速度和减轻白细胞降低的程度。提示钩吻对Ｃｙ化疗小鼠的造血功能具有保护作用。
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| 关 键 词： | 钩吻属；环磷酰胺；肉瘤180；白细胞计数 |
Hernopoietic protection of gelsemium elegans benth in cyclophosphamide-treated mice |
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| Huang Lanqing Wang kun She Shangyang Zhou Liyuan Zhao Lijuan. Hernopoietic protection of gelsemium elegans benth in cyclophosphamide-treated mice[J]. Journal of Youjiang Medical College For Nationalities, 1994, 16(4): 5-7 |
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| Authors: | Huang Lanqing Wang kun She Shangyang Zhou Liyuan Zhao Lijuan |
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| Affiliation: | Huang Lanqing Wang kun She Shangyang Zhou Liyuan Zhao Lijuan Department of Microbiology,Youjiang Medical for National Minorities Bose,Guangxi,China |
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| Abstract: | Results of experimenting with extract of Gelsemium elegans Benth(GEB)on murine Sarcoma 180(S180)proved that extract of GEB could not inhibit thegrowth of murine Sarcoma 180(S180),nor enhanced the therapeutic effect ofcyclophosphamide(Cy)in S180 - bearing mice.It was shown that GEB could al-leviate the decrease in peripheral leukocyte counts induced by Cy,indicatingthat GEB could diminish the hematological toxicity of Cy.The precise mecha-nism of interaction between GEB and Cy remains to be elucidated. |
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| Keywords: | gelsemium cyclophosphamide sarcoma 180 leukocyte count |
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