早期直肠癌经肛局部切除术与根治术临床比较分析

目的 探讨早期直肠癌局部切除术的临床应用价值.方法 分析本组103例早期直肠癌患者分别行局部切除(63例) 或根治术(40例) 的疗效(5年及10年生存率) ,并观察两种术式术后并发症的出现率.结果 行局部切除术患者的5年、10年生存率分别为93.7%和84.1%;而行根治术患者的5年、10年生存率分别为97.5%和90%.两种术式的5年和10年生存率比较,差异无显著性意义(X2=0.006,P＞0.05;X2=0.071,P＞0.05),且局部切除术术后并发症的发生率(0) 明显低于根治术(30%,X2=9.78,P＜0.05).结论 对早期直肠癌行局部切除术,方法简单易行,术后并发症少,能提高患者术后生存质量.

Clinical comparative analysis of local excision per anus and radical surgery in treatment of early rectal cancer

Objective To evaluate local resection for the treatment of early rectal cancer in terms of long survival.Methods 103 cases of early rectal cancer underwent local resection(63 cases) or radical resection(40 cases).Long-term survival and postoperative complications were compared with each other.Results The 5 and 10 years survival rate were 93.7% and 84.1%for local resection and 97.5% and 90%for radical operation,respectively.The differences were not statistically significant(X2=0.006,P>0.05;X2=0.071,P>0.05).The postoperative complication developed in 0 for local resection,which was statistically lower than that for radical operation of 30%(X2=9.78,P<0.05).Conclusions The local resection in early rectal cancer is simple and easy to perform,with a long-term survival comparable to radical resection and much lower postoperative morbidity.