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Dynamics of the Recovery Period in Rats Exposed to Global Cerebral Ischemia
Authors:V. V. Drozd  V. A. Kosolapov  O. V. Ostrovskii  A. A. Spasov
Affiliation:(1) Department of Pharmacology, Volgograd Medical Academy, Russia
Abstract:Global cerebral ischemia-reperfusion was modeled by thermocoagulation of the vertebrobasilar arteries followed by occlusion of both carotid arteries. Behavioral parameters, neurological status, and mnesic functions in rats were studied during the recovery period. It is concluded that this model of ischemia is reproducible and can be used for studying ischemia-reperfusion damages to the brain.
Keywords:cerebral ischemia  neurological status  behavioral reactions
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