Some derivatives of the 2-[4-pyrazolinyl]-1,3,4-thiadiazole system |
| |
Authors: | G Auzzi F Bruni M Clauser A Costanzo L Pecori Vettori B Ademollo |
| |
Abstract: | The synthesis of some 2-[5-amino-1-methyl-3-oxo-4-pyrazolynyl]-1,3,4-thiadiazole derivatives is accomplished by reacting 5-amino-1-methyl-3-oxopryrazolynyl-4-dithiocarbohydrazide with carboxylic acid derivatives. The structure of the compounds obtained is verified by means of 1H and 13C-N.M.R. spectra. Antimicrobial and antifungal activity of some of the described compounds was tested in a preliminary screening. |
| |
Keywords: | |
|
|