成人缺铁性贫血合并脑静脉血栓形成的临床特点及诊治

目的 探讨成人缺铁性贫血合并脑静脉血栓形成的临床特点及诊治。方法 对成人缺铁性贫血合并脑静脉血栓形成的临床特点及诊治进行回顾分析,并复习相关文献。结果 本研究报道的4例缺铁性贫血合并脑静脉血栓形成的患者均为女性,年龄33～47岁,缺铁性贫血的原因均为月经过多,其中1位33岁女性同时合并节食。4例患者否认肿瘤、凝血异常、自身免疫病、甲状腺功能异常病史,否认近期服用避孕药物、近期胃肠手术史及相关家族史等,筛查肿瘤、凝血功能、自身免疫、甲状腺功能等检查未见异常。4例患者均补铁治疗,2例患者经抗凝治疗后症状缓解,1例患者行支架治疗,1例患者经抗凝治疗后视力下降无缓解,予静脉支架置入术后症状未再进展。4例患者经补铁,抗凝或支架治疗后除1例抗凝治疗效果不佳未及时行支架术的患者预后差外,余3例均预后良好,未遗留神经系统症状。结论 缺铁性贫血为脑静脉血栓形成的可能原因之一,对于缺铁性性贫血患者,特别是女性患者如出现头痛,视物模糊等症状时,需注意并发脑静脉血栓形成的可能,如果能早期诊断,积极治疗,预后良好

Clinical characteristics,diagnosis and treatment of iron deficiency anemia complicated with cerebral venous thrombosis in adults

ObjectiveTo investigate the clinical characteristics, diagnosis and treatment of iron deficiency anemia with cerebral venous thrombosis in adults.Methods The clinical characteristics, diagnosis and treatment of iron deficiency anemia with cerebral venous thrombosis in adults were retrospectively analyzed, and the related literatures were reviewed.Results The four cases of iron deficiency anemia with cerebral venous thrombosis were all females aged 33～47 years. The causes of iron deficiency anemia were menorrhea, and 33 years old patient of four patients was on diet at the same time. Four patients denied the medical history of tumors, coagulation abnormalities, autoimmune diseases, thyroid dysfunction. They denied recent use of contraceptives, recent history of gastrointestinal surgery and related family history. We screened for tumor-related examinations, coagulation function, examination of autoimmune diseases, thyroid function and the above examinations were not abnormal. Four patients were treated with iron supplementation. The Symptoms of two patients were relieved after anticoagulation treatment, one patient was treated with stent. The vision loss of one patient had no relief after anticoagulation treatment, and the symptoms did not progress after intravenous stent implantation. After iron supplementation, anticoagulation or stent treatment, the prognosis of three patients was good, except for one patient who had poor anticoagulation effect and did not undergo stenting in time.Conclusion Iron deficiency anemia was one of the possible causes of cerebral venous thrombosis. For patients with iron deficiency anemia, especially female patients, we needed to pay attention to the possibility that the diagnosis of cerebral venous thrombosis when they had symptoms such as headache and blurred vision. If these patients could be diagnosed early and treated actively, the prognosis was good