Safety and immunogenicity of a booster dose of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine coadministered with DTPw-HBV/Hib and poliovirus vaccines |
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| Authors: | Bermal Nancy Szenborn Leszek Edison Alberto Hernandez Marina Pejcz Jerzy Majda-Stanislawska Ewa Gatchalian Salvacion Fanic Aurélie Dieussaert Ilse Schuerman Lode |
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| Affiliation: | Research Institute for Tropical Medicine, Filinvest Corporate City, Alabang, Muntinlupa City, Philippines. nnbid02@yahoo.com |
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| Abstract: | The safety and reactogenicity profiles of the 10-valent pneumococcal conjugate vaccine, PHiD-CV, and 7vCRM were comparable within the Philippines and Poland when coadministered as a booster dose with DTPw-HBV/Hib and poliovirus vaccines to toddlers primed with the same vaccines. Robust immune responses for all 10 vaccine pneumococcal serotypes and protein D following PHiD-CV booster vaccination were indicative of effective priming. |
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