| 先锋必对兔眼视网膜的毒性实验研究 |
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| 引用本文： | 杨安怀 李永平. 先锋必对兔眼视网膜的毒性实验研究[J]. 皖南医学院学报, 1999, 18(2): 97-98 |
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| 作者姓名： | 杨安怀 李永平 |
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| 作者单位： | 湖北医科大学附属第一医院眼科!430060(杨安怀)，中山医科大学眼科中心(李永平，易玉珍) |
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| 摘 要： | 为探讨先锋必对视网膜的毒性作用和评估玻璃体内注射先锋必的安全剂量，采用眼底镜观察及光镜、电镜技术对注射3种不同剂量先锋必的兔视网膜标本进行观察。结果：5～10mg先锋必注射后兔眼视网膜未发现明显异常，20mg剂量注射后视网膜损伤仅局限光感受器外节。提示玻璃体腔注射先锋必的安全剂量5～10mg。
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| 关 键 词： | 先锋必 视网膜 中毒 兔 |
Retinal Toxicity of Intravitreal Cefoperazone in Rabbits |
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| Yang Anhuai,Li Yongping, Yi Yuzhen. Retinal Toxicity of Intravitreal Cefoperazone in Rabbits[J]. Acta Academiae Medicinae Wannan, 1999, 18(2): 97-98 |
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| Authors: | Yang Anhuai Li Yongping Yi Yuzhen |
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| Abstract: | In order to explore retinal toxicity and to estimate "safe dosage" of cefoperazone injected into vitrina,rabbits,divided into 3 dosage groups and 1 control group, were investigated. The results showed that in 5-10mg groupe the retinal damages were not observed while in 20mg group,the retinal damages were confined in outer layers of retina. The results demonstrated that safe donge of intravitreal cefoperazone were 5-10mg. |
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| Keywords: | cefoperazone retina toxicity rabbits |
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