| 舍曲林与氟西汀治疗抑郁症双盲对照研究 |
| |
| 引用本文： | 丁宝坤,秦晓霞.舍曲林与氟西汀治疗抑郁症双盲对照研究[J].临床精神医学杂志,1998,8(2):72-73. |
| |
| 作者姓名： | 丁宝坤 秦晓霞 |
| |
| 作者单位： | 中国医科大学第三临床学院，中国医科大学心理卫生医院 |
| |
| 摘 要： | 采用１０周随机双盲平行对照方法，研究舍曲林与氟西汀对抑郁症的治疗情况，对６３例病人采用ＨＡＭＤ、ＨＡＭＡ和ＳＥＣＬ评定。结果发现，两组药物治疗后ＨＡＭＤ评分均较疗前有明显下降，第１０周减分率舍曲林组为８１．８％，氟丁汀组为７８．１％，两组副反应均较小，组间无显著差异。作者就抑郁症病人的治疗问题提出讨论，认为ＳＳＲＩｓ类药物较好。
|
| 关 键 词： | 舍曲林 氟西汀 抑郁症 治疗 |
A double blind controlled study of depression treated with sertraline and fluoxetine |
| |
| Ding Baokun,et al..A double blind controlled study of depression treated with sertraline and fluoxetine[J].Journal of Clinical Psychological Medicine,1998,8(2):72-73. |
| |
| Authors: | Ding Baokun |
| |
| Institution: | Ding Baokun,et al.The Third Clinical College of Chinese Medical University,Shenyang 110032 |
| |
| Abstract: | Objective:To compare the efficacy and side effects of sertraline and fluoxetine in major depression. Method:63 patients with major depression were treated in a double blind controlled study at the different stages of ten weeks. Sertraline was compared with fluoxetine. HAMD, HAMA and SECL were used to analyse the improvement of the patients. Results:Compared with premedication, the reduction of HAMD was significant in both of these two groups at the end of the ten weeks: sertraline reductive ratio was 81 8%, fluoxetine was 78 1%. The side effects were slight, and there was no significant difference between these two groups. Discussion:Sertraline and fluoxetine are both effective antidepressants with few side effects.SSRIs may be drugs of choice in the treatment of depression. |
| |
| Keywords: | Sertraline Fluoxetine Depression |
| 本文献已被 CNKI 维普 等数据库收录！ |
