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A new subdural probe for combined intracranial pressure (ICP) and cerebral blood flow (CBF) monitoring
Authors:E. Keller  A. Nadler  P. Niederer  Y. Yonekawa  H.-G. Imhof
Affiliation:(1) Department of Neurosurgery, University of Zurich, Switzerland, CH;(2) Institute of Biomedical Engineering, University and ETH of Zurich, Switzerland, CH
Abstract:Summaey We report the development of a new subdural probe for combined intracranial pressure (ICP) and cerebral blood flow (CBF) monitoring with near infrared spectroscopy (NIRS) and indocyanine green (ICG) dye dilution. For NIRS a conventional subdural ICP monitoring probe was supplied with two fiber bundles and 90-degree prisms. Injections of 25thinspmg ICG were performed. Regional values for the mean transit time of ICG (rmttICG), cerebral blood flow (rCBF) and cerebral blood volume (rCBV) were calculated. With prototypes of the probe in two patients with intracerebral haemorrhage 18 comparative measurements obtained simultaneously with conventional NIRS (optodes placed on the skin) and the subdural NIRS probe were performed. The new subdural NIRS probe allows combined monitoring of ICP and cerebral hemodynamics in the brain directly, without the influence of extracerebral tissue.
Keywords:: Cerebral blood flow   indocyanine green dye dilution   intracranial pressure   near infrared spectroscopy.
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