解脲支原体与人型支原体体外耐药性探讨

目的 探讨解脲支原体(UU)和人型支原体(Mh)的耐药性，指导临床合理用药。方法 采用体外培养的方法，对244例UU阳性、86例Mh阳性的泌尿生殖道感染患者，做药物敏感试验，检测UU与Mh对抗生素的耐药性。结果 对UU、Mh敏感的药物分别是普那霉素(90．91％)、交沙霉素(86．06％)、强力霉素(72．73％)。对红霉素、氧氟沙星、四环素的耐药率分别为52．42％、48．79％和45．15％。结论 对泌尿生殖道支原体(UU与Mh)感染可首选普那霉素、交沙霉素和强力霉素，不宜选用红霉素、氧氟沙星和四环素治疗。

Study on drug resistance of ureaplasma uralyiam and mycoplasma hominis

Objective To understand the drug resistance of ureaplasma uralyliam(UU)and mycoplasma hominis(Mh)for the purpose of rational use of antibiotics in clinical practice.Method By culture in vitro,the drug sensitive test of UU and Mh from 244 UU patients and 86 Mh patients was conducted to detect their drug resistance.Result The sensitive antibiotics were pristinamycin(90.91%),josamycin(86.06%) and doxycycline(72.73%),respectively.The resistance rates of the tested mycoplasma against erythromycin,ofloxacin and tetracycline were 52.42%,48.97% and 45.15%,respectively.Conclusion Pristinamycin,josamycin and doxycycline may be selected as drugs of the first choice to treat mycoplasma infections of urogenital tractis.It is unsuitable to use erythromycin,ofloxacin and tetracycline for this condition.