解剖M型超声评价室间隔缺损患者肺血管阻力的初步研究

目的：探讨解剖M型超声（AMM）对分析室间隔缺损（VSD）患者肺动脉机械特征及评价肺血管阻力（PVR）的价值。方法：应用AMM观测20例轻症VSD患者、18例重症VSD患者及20例正常人的主肺动脉运动曲线，测量主肺动脉短轴缩短率（PAFS）、主肺动脉外侧壁搏动幅度（PAWPA）、外侧壁快速扩张速率（R—DVR）及外侧壁快速缩短速率（R—CVR）。应用VSD跨隔压差结合肱动脉压计算出肺动脉收缩压，应用肺动脉血流时间间期法计算出PVR值。结果：VSD轻症组及重症组的PAFS、PAWPA、R—DVR及R—CVR均低于对照组，且重症组上述参数的减小幅度更显著（P〈0．05）。结论：AMM可无创评价肺动脉的力学特性，PAFS及PAWPA等参数可作为半定量评价VSD患者PVR的超声指标。

Anatomic M-mode echocardiographic evaluation for pulmonary vascular resistance in patients with ventricular septal defect

Objective:To explore the utility of anatomic M-mode echocardiographic(AMM) evaluation for pulmonary arterial mechanical characteristics and its relation to the severity of the increased pulmonary vascular resistance(PVR) in patients with ventricular septal defect(VSD).Methods:Routine echocardiography and AMM examination were performed on 20 healthy individuals and 38 patients with VSD who were divided into two groups according to the severity of PVR: patients with mild VSD(n=20) and patients with severe VSD...