| 幽门螺杆菌疫苗递送系统的研究进展 |
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| 引用本文： | 孙红武,刘唯,邹全明.幽门螺杆菌疫苗递送系统的研究进展[J].国外医学(药学分册),2009(6):431-434. |
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| 作者姓名： | 孙红武 刘唯 邹全明 |
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| 作者单位： | 国家免疫制品工程技术研究中心/第三军医大学医学检验暨药学院微生物及生化药学教研室; |
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| 摘 要： | 幽门螺杆菌感染是慢性胃炎、胃和十二指肠溃疡、胃肠癌等消化道疾病的主要病因。目前疫苗已成为控制幽门螺杆菌感染的一种有效手段，但需一定的递送系统才能发挥出预期药效。因此，疫苗递送系统成为近年来研究活跃的领域之一。本文总结了近年来幽门螺杆菌疫苗递送系统的研究进展，并主要对微粒、脂质体、冻干粉、复乳及凝胶、纳米疫苗等方面的研究进行综述。
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| 关 键 词： | 幽门螺杆菌 疫苗 递送系统 |
Helicobacter pylori vaccine delivery systems:research progress |
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| SUN Hong-wu,LIU Wei,ZOU Quan-Ming.Helicobacter pylori vaccine delivery systems:research progress[J].Foreign Medical Sciences(Section of Pharmarcy),2009(6):431-434. |
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| Authors: | SUN Hong-wu LIU Wei ZOU Quan-Ming |
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| Institution: | SUN Hong-wu,LIU Wei,ZOU Quan-Ming (National Engineering Research Center for Immunological Products/Department of Microbiology and Biochemical Pharmacy,Faculty of Laboratory Medicine & College of Pharmacy,the Third Military Medical University of PLA,Chongqing 400038,China) |
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| Abstract: | Helicobacter pylori (Hp) infection is the main cause of digestive tract diseases,such as chronic gastritis,gastroduodenal ulcer,gastrointestinal cancer and so on.Nowaday,vaccine has become an effective method to control Hp infection.However,it needs an ideal drug delivery system to achieve an optimal prophylactic effect.In recent years,the research on vaccine delivery system has become a quite active field.This review introduces the research progress in Hp vaccine delivery system,mainly focusing on micro-pa... |
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| Keywords: | Helicobacter pylori vaccine vaccine delivery system |
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