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室性早搏索他洛尔干预前后心率变异性、QT离散度变化
引用本文:董新,党寅虎,张超英,宋安齐,牛小麟.室性早搏索他洛尔干预前后心率变异性、QT离散度变化[J].中国现代医学杂志,2000,10(8):18-19.
作者姓名:董新  党寅虎  张超英  宋安齐  牛小麟
作者单位:西安医科大学第二附属医院心内科,710004
摘    要:为探讨索他洛尔对室性早搏患者心率变异性(HRV)及QT离散度(QTd)的影响,20例室性早搏患者服用了索他洛尔(80mg,2次/d)周,测定了用药前后的24h心率变异的时域指标及QTd,并与30例正常人比较。结果表明:室性早搏患者的HRV各指标均低于正常组(P〈0.05或〈0.01),QTd、QTcd增高(P〈0.001);索他洛尔治疗后HRV各指标增高(P〈0.05),并与正常对照组比较无显著意

关 键 词:室性早搏  索他洛尔  心率变异性  QT离散度  治疗

THE CHANGES OF SOTALOL ON HEART RATE BARIAILITY AND QT DISPERSION IN PREMATURE VANTRICULAR BEATS
Dong Xin,Dand Yinhu,Zhang Chaoyin,et al..THE CHANGES OF SOTALOL ON HEART RATE BARIAILITY AND QT DISPERSION IN PREMATURE VANTRICULAR BEATS[J].China Journal of Modern Medicine,2000,10(8):18-19.
Authors:Dong Xin  Dand Yinhu  Zhang Chaoyin  
Institution:Dong Xin,Dand Yinhu,Zhang Chaoyin,et al. Department of Cardiology,the Second Affiliated Hospital of Xi'an Medical University,Xi'an 710004
Abstract:To study effects of sotalol on heart rate variability (HRV) and QT dispersion (QTD). We measured 24 hours time domain indexes of HRV and QTD before and two weeks after treated with sotalol (80mg, bid) in 20 patients with premature ventricular beats, and compared with 30 health subjects. The results showed that the time domain indexes of HRV were significantly decreased in premature ventricular beats as compared with normal control group ( P <0.05 or 0.01), QTd, QTcd were significantly increased ( P <0.01). Use of sotalol could increase the levels of HRV ( P <0.05) and reduce QTd, QTcd ( P<0.05). Thus, use of sotalol in patients with ventricular arrhythmias could improve HRV and QTd.
Keywords:Sotalol  Heart Rate Variability  QT Dispersion
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