一期梅毒治疗后血清学追踪检测结果分析

目的　分析一期梅毒 (PS)治疗后血清学追踪检测结果变化及其相关影响因素。方法　对 87例PS患者治疗前和治疗后随访期内进行血清学TRUST和TPPA定量检测。结果　PS患者治疗后TRUST转阴时间为 9.1± 1.2个月 ;不同病程组患者TRUST转阴时间比较差异有显著性 (P <0 .0 5 ) ;治疗前血清滴度不同组及不同治疗方法组患者TRUST转阴时间比较差异均有高度显著性 (P均 <0 .0 1) ;2 4.7%PS患者治疗后TPPA转阴。结论　PS患者治疗后TRUST转阴时间为 9个月左右 ,影响因素有病程、治疗前血清滴度及治疗方法等 ;部分PS患者治疗后TPPA可转阴。

Analysis on Serology in the Treated Patients with Primary Syphilis

Objective To analyze the tracking results for serum antibodies in the treated patients with primary syphilis(PS) and the relat ed influence on the detection.Methods 87 patients with PS were quantitatively detected by TRUST and TPPA before and after treatment.Results By the end of about 9.1±1.2 months in the treate d patients with PS TRU ST had become negative.The time when TRUST had become negative was significant ly different because of the course of the disease( P <0.05) and the serology t iter before treatment( P <0.01) and the therapy( P <0.01).TPPA became negati ve in 24.7% of the treated patients with PS.Conclusion By the end of about 9 months in the treated pa tients with PS,TRUST become negative and the related infuenence included the co urse of the disease and the serology titer before treatment and the therapy.TPPA become negative in part of the treated patients with PS.