| 靶向释放智能纳米载体的研究进展 |
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| 引用本文： | 顾君彤,徐维平,陆杨,徐婷娟,黄向华,张勇强. 靶向释放智能纳米载体的研究进展[J]. 中国药业, 2012, 21(21): 1-3 |
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| 作者姓名： | 顾君彤 徐维平 陆杨 徐婷娟 黄向华 张勇强 |
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| 作者单位： | [1]安徽中医学院研究生部,安徽合肥230038 [2]安徽省立医院,安徽合肥230001 [3]中国科学技术大学,安徽合肥230026 |
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| 基金项目： | 安徽省学术和技术带头人及后备人选学术科研经贾资助,项目编亏：11040000M193 |
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| 摘 要： | 随着材料科学的进步,智能纳米载体在药物和基因靶向治疗方面取得了巨大的研究进展。智能纳米载体被化学信号、温度、pH等"触发器"激发后,能在特定部位响应性地释放药物或基因。该文从智能纳米载体的定义,不同类型靶向释放的智能纳米载体在药物和基因中的研究进展,靶向释放的智能纳米载体的不足及发展前景等方面进行综述。
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| 关 键 词： | 智能纳米载体 靶向释放 传输 药物 基因 |
Research Progress in Intelligent Nano-Carriers for Targeted Delivery |
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| Gu Juntong,Xu Weiping,Lu Yang,Xu Tingjuan,Huang Xianghua,Zhang Yongqiang. Research Progress in Intelligent Nano-Carriers for Targeted Delivery[J]. China Pharmaceuticals, 2012, 21(21): 1-3 |
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| Authors: | Gu Juntong Xu Weiping Lu Yang Xu Tingjuan Huang Xianghua Zhang Yongqiang |
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| Affiliation: | 1. Department of Postgraduates, Anhui University of Traditional Chinese Medicine, Hefei, Anhui, China 230038; 2. Anhui Provincial Hospital, Hefei, Anhui, China 230001; 3. University of Science and Technology of China, Hefei, Anhui, China 230026) |
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| Abstract: | With the advances in material science, intelligent nano-carriers for targeted drug and gene delivery have made tremendous progress. In response to stimuli including chemical molecules, temperature and pH, drugs and genes could be released from intelligent nano- carriers in targeted tissues and organs. This review contains three parts of intelligent nano- carriers, definition, research advance on different types of targeted delivery intelligent nano-carriers in drug and gene, and disadvantage and development prospect of intelli- gent nano-carriers for targeted delivery. |
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| Keywords: | intelligent nano - carriers targeted release delivery drug gene |
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