家蝇对菊酯类的抗性及增效剂的增效作用

本文测定了Ｄｅｃｉｓ－Ｒ、２ｃｌ－Ｒ和敏感品系（ＳＰ）家蝇头部乙酰胆碱酯酶（ＡＣｈＥ）的活力，溴氰菊酯、二氯苯醚菊酯、半胆碱（ＨＣ－３）、增效磷（ＳＶ１）、八氯二丙醚（Ｓ２）、苯基甲氨基甲酸酯（Ｓ３），杀那特（Ｓ４）对ＡＣｈＥ的抑制作用。结果表明，家蝇头部ＡＣｈＥ活力与抗性的形成有一定的关系，溴氰菊酯、二氯苯醚菊酯、Ｓ２对ＡＣｈＥ的抑制作用不明显，ＨＣ－３、ＳＶ１、Ｓ３和Ｓ４对抗性家蝇ＡＣｈＥ的抑

Synergism of Several Compounds to Pyrethroids in HouSefly

The synergism to Deltamethrin and Permethrin in high resistant (Decis-R and 2cl-R) and susceptible (SP) strains of houseflies by several inhibitors was determinded. Piperonyl butoxide (Pb), a microsomal oxidase inhibitor, synegrized two pyrethroids, although at different degrees, in both Decis -R and 2cI-R strains. The pretreatment of the Decis-R strain with Pb increased the effectiveness of Deltamethrin by 629- fold The SR values of 2cl-R for Permethrin was 46.93. It in- dicated that the oxidizing metabolism play an important role in the resistant mechanism against Pyrethroids in the houseflies. The activity of acetylcholi-nesterase (AChE) was determined in different strains of the housefly. The I_(50) of Ache of resis- tant flies for HC-3,SV_1, S_3.and S_4 are higher than those of the susceptible ones. The insensitivity of the Ache to these in- hibitors may be one of causes of the housefly resistance a- gainst Pyrethroids. Though Pb is the strongest synergist among several syn- ergists studied, the application of Pb has been limited because of its costliness and chemical instability. The synergism of. S_2 for Deltamethrin and Permethrin is higher in three strains. S_2 is considered as a synergist of great exploiting prospects.