Lead,mercury, and cadmium in blood and their relation to diet among Swedish adults |
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| Institution: | 1. Laboratory of Chemistry and Utilization of Animal Production Resources, Graduate School of Agricultural Science, Faculty of Agriculture, Kobe University, Japan;2. Laboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University, Japan;3. Laboratory of Biochemistry Frontiers, Graduate School of Agricultural Science, Faculty of Agriculture, Kobe University, Japan;1. Department of Pathology, Charles University, Biomedical Center, Faculty of Medicine in Plzen and Charles University Hospital Plzen, Czech Republic;2. Department of Pathology, Charles University, Medical Faculty and Charles University Hospital Plzen, Czech Republic;3. Institute of Pathology, Friedrich‐Alexander University Erlangen‐Nürnberg, Erlangen, Germany;4. Department of Pathology, Louis Pasteur University Hospital, Kosice, Slovakia;5. Red Cross Hospital Kochi, Kochi, Japan;1. East London Foundation NHS Trust, 5-7 Rush Court, Bedford MK40 3JT, UK;2. University College, London, UK;3. King''s College, London, UK |
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| Abstract: | The aim of the present study was to examine the body burden of lead (Pb), mercury (Hg), and cadmium (Cd) in blood among Swedish adults and the association between blood levels, diet and other lifestyle factors.The study was based on a subgroup (n = 273) of the national survey Riksmaten 2010–2011 (4-day food records and questionnaire). Lead, Hg, and Cd were measured in whole blood, and Cd additionally in urine, by mass or fluorescence spectrometry methods.The median values (5–95th percentiles) of the metals in blood were as follows; Pb: 13.4 (5.8–28.6) μg/L, Hg: 1.13 (0.31–3.45) μg/L, and Cd: 0.19 (0.09–1.08) μg/L. All three metals increased with increasing age. Lead levels in blood were positively associated with intakes of game and alcohol, Hg was related to fish intake, and blood Cd related to smoking and low iron stores and to a low meat intake.Body burdens of the studied metals were generally below health based reference values, but several individuals had blood Pb levels above the reference point for possible nephrotoxic and developmental neurotoxic effects. As health effects cannot be excluded, individuals with high Pb exposure should aim at decreasing their body burden, both from food and from other exposure routes. |
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| Keywords: | Heavy metals Lead Mercury Cadmium Diet Blood |
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