A hybridoma secreting a neutralising monoclonal antibody to egg drop syndrome 1976 virus |
| |
| Authors: | A P Mockett T D Brown P J Davis |
| |
| Affiliation: | Houghton Poultry Research Station, Houghton, Huntingdon, Cambridgeshire, England. |
| |
| Abstract: | A hybridoma (HPRS/AM/1) secreting neutralising antibody to Egg drop syndrome 1976 virus strain D61 was established. This monoclonal antibody also neutralised two other strains tested thereby showing that all the strains possess at least one common antigenic determinant which is important in infection. However, this epitope was not involved in haemagglutination. The antigen was identified in the nuclei of infected chick kidney cells by an indirect fluorescent antibody test. |
| |
| Keywords: | |
|
|
