毒蕈中毒并发多器官功能衰竭1例报告并文献复习

目的：报道1例应用血液净化治疗毒蕈中毒并多器官功能衰竭病例，探讨毒蕈中毒并发多器官功能衰竭的救治方法及原理。方法：患者接受血浆置换，隔日1次，联合血液灌流及血液透析序贯血液净化治疗，并辅以激素冲击、抗感染等积极对症支持治疗。结果：治疗后患者脱离生命危险，生命体征平稳，肝功能、肾功能和凝血等均有改善。结论：早期应用血浆置换联合血液灌流及血液透析序贯血液净化可有效治疗毒蕈中毒并发多器官功能衰竭及血栓性微血管病，并改善预后。

Mushroom poisoning complicated with multiple organ disfunction syndrome:A case report and literature review

Objective:To report one case of mushroom poisoning complicated with multiple organ disfunction syndrome treated by sequential blood purification,and to explore the treatment method and principle of mushroom poisoning complicated with multiple organ disfunction syndrome.Methods:Hemoperfusion was performed in the patient,once every other day,combined with sequential blood purification of hemoperfusion and hemodialysis, and supplemented by hormone therapy and anti-infection.Results:The patient was out of danger,and the vital signs were stable;liver function,kidney function and blood routine were recovered.Conclusion:Early application of hemoperfusion combined with sequential blood purification can effectively treat the mushroom poisoning complicated with multiple organ disfunction syndrome and thrombotic microangiopathy,and improve the prognosis.