药物性肝损伤药学实践探索

摘 要 目的：探索疾病治疗药学服务模式的新思路。方法: 临床药师积极参与1例混合型肝损伤患者的药学实践，在不良反应分析、病因机制探讨、治疗药物选择以及危险因素预防等方面提供临床药学服务。结果: 临床药师与医师紧密合作，及时发现问题并在药品的选择、剂量的确定、疗效的评估、指标的监测等方面进行用药分析，及时调整药物治疗方案。患者肝功能逐渐恢复，病情好转后出院。结论: 临床药师通过参与药学实践提供临床药学服务，有助于提高患者用药的安全性和有效性，同时也是加强药师自身学习、培养临床思维和实践能力的有效途径。

Exploration of Pharmaceutical Practice for Drug induced Liver Injury

ABSTRACT Objective: To explore a new way of pharmaceutical service mode for disease treatment. Methods: Clinical pharmacists actively participated in the pharmaceutical care for a patient with mixed liver injury, and provided clinical pharmaceutical services through the adverse reaction analysis, etiological mechanisms exploration, therapeutic drugs selection and risk factors prevention. Results: Clinical pharmacists cooperating closely with physicians helped to identify problems in time, and then the medication analysis in the fields of drug selection, dose determination, efficacy evaluation and indicators detection was performed, so that the strategies on medicine treatment could be adjusted timely as the disease progressed. With the gradual recovery of liver function, the patient discharged after the conditions were improved. Conclusion:By participating in pharmaceutical practice, clinical pharmacists can provide clinical pharmaceutical service, which is helpful to safety improvement and efficiency of drug administration. It is also an effective way to enhance the learning ability of pharmacists, and cultivate their clinical thinking and practice capacity.