立体定向放射治疗三叉神经痛

目的 :探讨立体定向放射治疗三叉神经痛的方法、疗效。方法 :对 3 0例三叉神经痛患者实施头戴面罩 ,单次、非共面、多角度的立体定向放射治疗。靶点数 2个 ,准直器 5mm ,边周剂量 60～ 75Gy ,参考剂量曲线 85 %～ 90 %。结果 :随访 1个月～ 2 2个月 ,12～ 2 4h症状减轻或缓解者 6例 ,1～ 3个月显效者 2 0例 ,4例效果不明显 ,有效率达 86 7%。 1例出现患侧面部麻木 ,1例首次治疗效果不佳 ,再次调整剂量后效果显著。结论 :立体定向放射治疗三叉神经痛是一种有效的治疗方法。

Preliminary results of stereotactic radiotherapy for trigeminal neuralgia

Objective: To discuss the results of stereotactic radiotherapy (SRT) for trigeminal neuralgia.Methods: Thirty patients with trigeminal neuralgia wearing face cover were treated with noncoplanarity fractional stereotactic radiotherapy.The patients received 2 target regions and peripheral does of 60～75 Gy.5 mm collimator and isodose curves referred to ranged from 85%～90%.Results: The follow up period ranged from 1 to 22 months.Among the patients,6 patients symptoms were lightened or eased up over 12～24 hours,20 patients received a marked effect over 1～3 months,4 patients' treatment effects were not obvious.The effect rate reached 86 7%.A patient occurred anesthesia in sick face,a patient had not a well effect in the first treatment,but in the second treatment he received a approving results.Conclusion: The present study suggests that SRT be an effective treatmnet for trigeminal neuralgia.