Mesenchymal stem cells in the infarcted heart |
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| Authors: | Jain Mohit Pfister Otmar Hajjar Roger J Liao Ronglih |
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| Affiliation: | Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02118, USA. |
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| Abstract: | A loss of functional cardiomyocytes forms the cellular basis of cardiac dysfunction and heart failure. Stem cell based repletion of scarred myocardial tissue and regeneration of cardiomyocytes have been proposed as a potential treatment of ventricular dysfunction. In this review, we provide an overview of recent studies utilizing mesenchymal stem cells in cardiac regeneration and post-myocardial infarct therapy. |
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