儿童发作性睡病的临床与视频脑电图特征

目的 探讨小儿发作性睡病的临床与视频脑电图特征。方法 对15例发作性睡病患儿进行睡眠脑电图监测，结合临床特点予以诊断，采用利他林治疗。结果 15例患儿均有过度或发作性的白日睡眠，7例伴猝倒，3例出现睡眠瘫痪，4例出现睡眠幻觉，3例伴有自动样行为。睡眠脑电图监测显示12例平均睡眠潜伏期〈5min，有2次或2次以上直接进入快速眼动相睡眠。经过治疗，有10例白天过度睡眠改善。结论 视频脑电图有助于发作性睡病的诊断。利他林治疗有确切疗效。

The clinical and video-EEG characteristics of narcolepsy of 15 cases in childhood

ObjectiveTo evaluate of the clinical and video-EEG characteristicse of narcolepsy in child hood.Methods15 cases of narcoleptic children were performed sleep EEG montoring were diagnosed combining with the clinical characteristics of narcolepsy and were treated with methyphenidate.ResultsAll the patients manifested with excessive daytime sleepness,cataplexy appeared in 7 cases,and sleep paralysis in 3 cases,hypnagogic hallucination in 4 cases,and automatic behavior in 3 cases.Sleep EEG monitoring demonstrstaed a short mean sleep latency(<5 minutes) and two or more sleep onset REM periods(SOREMPs) in 15 cases methyphenidate were adminstered in 15 cases.The excessive daytime sleepiness had been improved in 10 cases.ConclusionsVideo-EEG exmination can help diagnose narcolepsy,methyphenidate is effective as an assistant therapy for narcolepsy.