| As2O3诱导KB和Tca8113细胞分化与包壳蛋白表达的关系 |
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| 引用本文： | 刘思思,鲁大鹏.As2O3诱导KB和Tca8113细胞分化与包壳蛋白表达的关系[J].北京口腔医学,2010,18(1):8-10. |
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| 作者姓名： | 刘思思 鲁大鹏 |
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| 作者单位： | 首都医科大学口腔医学院,北京,100050;首都医科大学口腔医学院,北京,100050 |
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| 基金项目： | 北京市留学人员科技活动择优资助市优秀项目，北京市卫生局留学回国人员科研专项经费，教育部留学回国人员科研启动基金 |
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| 摘 要： | 目的探讨As2O3对人口腔鳞癌KB和Tca8113细胞诱导分化的作用与包壳蛋白（involucfin）表达的关系。方法用免疫荧光技术观察As2O3诱导KB和Tca8113细胞分化前后包壳蛋白的表达和变化。结果包壳蛋白在As2O3对人口腔鳞癌KB和Tea8113细胞诱导分化后比其诱导分化前包壳蛋白表达增高。结论As2O3诱导口腔鳞癌分化可导致包壳蛋白表达增高，其作用机理尚不清楚。
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| 关 键 词： | As2O3 KB细胞 Tca8113细胞 包壳蛋白 诱导分化 |
The relationship between involucrin expression and the differentiation of KB cells and Tca8113 cells after induction by arsenic trioxide |
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| LIU Si-si,LU Da-peng.The relationship between involucrin expression and the differentiation of KB cells and Tca8113 cells after induction by arsenic trioxide[J].Beijing Journal Of Stomatology,2010,18(1):8-10. |
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| Authors: | LIU Si-si LU Da-peng |
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| Institution: | LIU Si-si,LU Da-peng.Capital Medical University School of Stomotology,Beijing 100050,China |
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| Abstract: | Objective To investigate the relationship between the involucrin expression and the differentiation of KB cells and Tca8113 cells after induction by arsenic trioxide(As2O3).Methods The expressions of involucrin in KB and Tca8113 cells before and after induction by As2O3 were examined by immunofluorescence staining technique.ResultsAfter the induction by As2O3,KB cells and Tca8113 cells were differentiated and the expression of involucrin protein was upregulated compared with before induction.Conclusion The ... |
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| Keywords: | As2O3 |
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