Prevalence of psychiatric disorders in the first trimester of pregnancy and factors associated with current suicide risk |
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Authors: | Dayana Rodrigues Farias,Thatiana de Jesus Pereira Pinto,Marcella Martins Alves Teofilo,Ana Amé lia Freitas Vilela,Juliana dos Santos Vaz,Antonio Egidio Nardi,Gilberto Kac |
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Affiliation: | 1. Nutritional Epidemiology Observatory, Department of Social and Applied Nutrition, Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, RJ, Brazil;2. Graduate Program in Nutrition, Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, RJ, Brazil;3. Institute of Psychiatry, School of Medicine, Federal University of Rio de Janeiro, National Institute for Translational Medicine (INCT-TM), Brazil |
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Abstract: | This study aimed to describe the prevalence of psychiatric disorders and to identify the factors associated with Current Suicide Risk (CSR) in the first trimester of pregnancy. The Mini-International Neuropsychiatric Interview (M.I.N.I.) was employed to diagnose mental disorders in 239 women enrolled in a prospective cohort in Rio de Janeiro, Brazil. Serum lipids, leptin and socio-economic status were the independent variables. CSR, the dependent variable, was entered as binary (yes/no) variable into crude and adjusted Poisson regression models with robust variances. CSR was found to be the main psychiatric syndrome (18.4%), followed by agoraphobia (17.2%), major depressive disorder (15.1%) and generalized anxiety disorder (10.5%). Women with CSR showed higher mean levels of cholesterol (169.2 vs. 159.2; p=0.017), high density lipoprotein (50.4 vs. 47.7; p=0.031) and low density lipoprotein (102.8 vs. 95.6; p=0.022) when compared to women without CSR. The adjusted regression model showed a higher prevalence ratio (PR) of CSR among pregnant women with generalized anxiety disorder (PR=2.70, 95% CI: 1.36–5.37), with ≥two parturitions (PR=2.46, 95% CI: 1.22–4.93), and with major depressive disorder (PR=2.11, 95% CI: 1.08–4.12). We have shown that generalized anxiety disorder, major depressive disorder and higher parity are associated with CSR in the first trimester of pregnancy. |
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Keywords: | Suicide Depressive disorder Anxiety Agoraphobia Pregnancy Women Parity |
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